Generic Name: Doxophylline 400mg
Company Name: Square Pharmaceuticals Limited
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Indications of Flindof 400
Asthma and chronic obstructive pulmonary disease symptoms can be treated and prevented with the help of Flindof $00. (a lung disorder in which the flow of air to the lung is blocked). It facilitates airway relaxation, which opens up the airway and facilitates better breathing.
Pharmacology
The drug doxophylline is a brand-new bronchodilator. The presence of a dioxolane group in position 7 distinguishes it from Theophylline structurally. Doxophylline relaxes bronchial smooth muscle by inhibiting phosphodiesterase 4 selectively. Doxophylline, on the other hand, appears to have lower affinities for adenosine A1 and A2 receptors than Theophylline.
Dosage & Administration
If a daily dose of 400 mg of Doxophylline is required, the Doxophylline SR tablet should be taken once daily or as directed by a physician.
Interaction of Flindof 400
Other xanthine derivatives should not be taken together with doxophylline. Xanthines have been shown to have toxic synergism with ephedrine. Concomitant therapy with troleandomycin, lincomycin, clindamycin, allopurinol, cimetidine, ranitidine, propranolol, and anti-flu vaccine, as with other xanthines, may reduce xanthine hepatic clearance, resulting in an increase in blood levels.
Contraindications
In acute myocardial infarction, doxophylline is contraindicated. Patients with hypotension, lactating women, and patients who have shown hypersensitivity to its components are also advised against taking it.
Side Effects of Flindof 400
Doxophylline rarely causes serious side effects, but it can have the same effects as taking too much caffeine. Nausea, vomiting, headaches, upset stomach, and heartburn are some of the symptoms.
Pregnancy & Lactation
Animal reproduction studies show that doxophylline has no effect on reproduction capacity or causes fetal harm when given to pregnant animals. However, because there is limited experience with xanthines during pregnancy in humans, they should only be given to pregnant women if absolutely necessary. Doxophylline should not be taken by nursing mothers.
Precautions & Warnings
A number of known variables influence the half-life of xanthine derivatives. Patients with liver disease, congestive heart failure, and those taking certain other drugs such as erythromycin, troleandomycin, lincomycin, allopurinol, cimetidine, propranolol, and the anti-flu vaccine may experience a delay. In these cases, a lower Doxophylline dose may be required.
Storage Conditions
Store below 30°C, away from light, in a cool, dry place. Keep out of children's reach.
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